Primary Lymphoma of the Trachea With Morphologic and Immunophenotypic Characteristics of Low-Grade B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue
- 1 January 1992
- journal article
- case report
- Published by Wolters Kluwer Health in The American Journal of Surgical Pathology
- Vol. 16 (1) , 71-75
- https://doi.org/10.1097/00000478-199201000-00011
Abstract
A patient with primary extranodal lymphoma arising in the trachea presented with severe upper airway obstruction. The tumor was localized at presentation. The patient has remained disease-free for 12 months following surgical resection and local radiation treatment. The tumor had distinctive morphologic features characteristic of low-grade lymphomas of mucosa-associated lymphoid tissue (MALT), including a diffuse infiltrate of small lymphocytes and centrocyte-like cells surrounding reactive follicles, with plasmacytoid differentiation, and lympho-epithelial lesions. The tumor cells expressed monotypic immunoglobulin but not CD5 or CD10. This case provides evidence that primary lymphomas of the trachea in some cases are tumors of mucosa-associated lymphoid tissue.Keywords
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