Enhancement of rectal absorption of insulin using salicylates in dogs
- 1 March 1983
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 35 (3) , 148-151
- https://doi.org/10.1111/j.2042-7158.1983.tb04294.x
Abstract
Sodium salicylate and 5-methoxysalicylate both increased the rectal absorption of insulin in dogs when co-administered with insulin in various formulations. Microenema formulations containing 4% gelatin showed the highest insulin biavailability of the formulations studied whereas microenemas (without gelatin) and suppository formulations were not as effective in enhancing the rectal absorption of insulin.This publication has 10 references indexed in Scilit:
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