Highly selective action of triphosphate metabolite of 4′-ethynyl D4T: A novel anti-HIV compound against HIV-1 RT
- 31 March 2007
- journal article
- Published by Elsevier in Antiviral Research
- Vol. 73 (3) , 185-191
- https://doi.org/10.1016/j.antiviral.2006.10.002
Abstract
No abstract availableKeywords
This publication has 26 references indexed in Scilit:
- Anti-Human Immunodeficiency Virus Type 1 Activity and Resistance Profile of 2′,3′-Didehydro-3′-Deoxy-4′-Ethynylthymidine In VitroAntimicrobial Agents and Chemotherapy, 2005
- Novel 4′-Substituted Stavudine Analog with Improved Anti-Human Immunodeficiency Virus Activity and Decreased CytotoxicityAntimicrobial Agents and Chemotherapy, 2004
- Investigating the effects of stereochemistry on incorporation and removal of 5-fluorocytidine analogs by mitochondrial DNA polymerase gamma: comparison of d- and l-D4FC-TPAntiviral Research, 2004
- Phosphorylation of Pyrimidine l-Deoxynucleoside Analog DiphosphatesJournal of Biological Chemistry, 2002
- Antitumor Activity and Pharmacokinetics of TAS‐106, l‐(3‐C‐Ethynyl‐β‐D‐ribo‐pentofuranosyl)cytosineJapanese Journal of Cancer Research, 2001
- A New Antitumor Nucleoside, 1-(3-C-Ethynyl-β-d-ribo-pentofuranosyl)-cytosine (ECyd), Is a Potent Inhibitor of RNA SynthesisNucleosides and Nucleotides, 1999
- Pre-Steady-State Kinetic Characterization of Wild Type and 3‘-Azido-3‘-deoxythymidine (AZT) Resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Implication of RNA Directed DNA Polymerization in the Mechanism of AZT ResistanceBiochemistry, 1997
- Comparative Enzymatic Study of HIV-1 Reverse Transcriptase Resistant to 2‘,3‘-Dideoxynucleotide Analogs Using the Single-Nucleotide Incorporation AssayBiochemistry, 1997
- Enzymatic Characterization of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Resistant to Multiple 2′,3′-Dideoxynucleoside 5′-TriphosphatesJournal of Biological Chemistry, 1995
- Mechanism of HIV reverse transcriptase: enzyme-primer interaction as revealed through studies of a dNTP analog, 3'-azido-dTTPBiochemistry, 1990