Relationship between chromosome aberrations at the first cleavage metaphases and postimplantation loss in dominant lethal mutations induced by isopropyl methanesulfonate.

Publisher Website
Google Scholar
Abstract
A high dose (200 mg/kg) of isopropyl mathanesulfonate (iPMS) induced a high frequency of postimplantation loss in postmeiotic male may be germ cell stages, but the frequency of eggs with chromosome aberrations observed at the 1st cleavage metaphases was very low. The postimplantation loss in dominant lethal mutations induced by iPMS may be mainly attributable to the alteration of subchromosome material at the 1st cleavage metaphases.

This publication has 0 references indexed in Scilit: