Studies of the Effect of Dimethylsulfoxide on Permeability of Dermal Connective Tissue.

Abstract
Summary Dimethylsulfoxide (DMSO) did not enhance tissue permeability at concentrations of 0.2, 2 and 5% when tested by the spreading method. In contrast, a slight inhibition of permeability (about 6%) was observed at a concentration of 0.2%. Its enhanced effect on skin “permeability” at a concentration of 50% was apparently due to tissue damage.