Platelet Storage in Glow Discharge‐Treated Polyvinylchloride Bags: Effects of a Plasticizer on Platelet Hypotonic Shock Response

1 November 1984

journal article
research article
Published by Wiley in Vox Sanguinis

Vol. 47 (5) , 330-334
https://doi.org/10.1111/j.1423-0410.1984.tb04135.x

Abstract

The effect of a plasticizer (DEHP [di-(2-ethylhexyl)phthalate]) of PVC [polyvinyl chloride] blood bags on [human] platelet response to hypotonic shock was examined. The response of the platelet concentrate (PC), stored in the bag in which DEHP elution was prevented by glow-discharge treatment, did not change until 72 h of storage. During PC storage in control bags or in plasma containing DEHP, the response decreased approximately linearly. The time course of DEHP incorporation into platelet agreed well with that of the decrease of the response to hypotonic shock.

This publication has 2 references indexed in Scilit:

Prevention of Leakage of Di‐(2‐ethylhexyl)phthalate from Blood Bags by Glow Discharge Treatment and Its Effect on Aggregability of Stored Platelets
Vox Sanguinis, 1983
The Platelet Response to Hypotonic Shock. Its Value as an Indicator of Platelet Viability After Storage
Transfusion, 1974