Selection of variants of Gram–negative bacteria with elevated production of type 1 β-lactamase
- 1 June 1983
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Antimicrobial Chemotherapy
- Vol. 11 (6) , 577-581
- https://doi.org/10.1093/jac/11.6.577
Abstract
Variants of Pseudomonas aeruginosa, Citrobacter freundiiand Enterobacter cloacae were isolated that produced elevated levels of type 1 β-lactamase. The variants were readily isolated on antibiotic-containing agar and showed resistance to a wide range of β-Mactam antibiotics including some regarded as being relatively stable to the β-lactamase produced.Keywords
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