Occurrence of the periodic acid‐Schiff positive granular leucocyte (PAS‐GL) in some fishes and its significance

Abstract
Preparations of peripheral blood of 58 species of fish, mostly teleosts, were examined for the presence of granulocytes. Heterophils are commonly found but eosinophils are rare and metachromatic basophils never seen. Granulocytes (PAS‐GL) with periodic acid‐Schiff positive granules, were observed in 30 species representing marine and freshwater, and ‘primitive’ and ‘advanced’ types. It is postulated that the PAS‐GL is the piscine forerunner to the heparin and histamine‐containing metachromatic basophil/mast cell of higher vertebrates.