Mutation induction by high-density, 50-Hz magnetic fields in human MeWo cells exposed in the DNA synthesis phase
- 1 January 1997
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology
- Vol. 71 (1) , 75-79
- https://doi.org/10.1080/095530097144445
Abstract
Exposure of cultured human MeWo cells to highdensity (400 mT at 50 Hz) extremely low frequency magnetic fields (ELF-MF) induced mutations in the hypoxanthineguanine phosphoribosyl transferase gene. Mutation induced by the ELF-MF increased during the DNA-synthesis phase in synchronously growing cells. DNA replication errors and/or disturbance of the mismatch repair systems caused by exposure to ELF-MF may be involved in the mutagenic effect.Keywords
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