Induction of colorectal squamous cell carcinomas in rats by dextran sulfate sodium
- 1 January 1982
- journal article
- research article
- Published by Oxford University Press (OUP) in Carcinogenesis: Integrative Cancer Research
- Vol. 3 (3) , 353-355
- https://doi.org/10.1093/carcin/3.3.353
Abstract
ACI rats, 15 males and 15 females, were fed a diet containing 1% dextran sulfate sodium for 660 days. Twenty two of 29 surviving rats developed intestinal tumors between 288 and 660 days. Most tumors consisted of papillomas, and 4 squamous cell carcinomas were also induced, in addition to adenomas and adenocarcinomas. No intestinal tumors were observed in rats of the control group.This publication has 0 references indexed in Scilit: