Potential role of the dynamic properties of whole blood coagulation in assessment of dosage requirements in haemophilia
- 26 June 2003
- journal article
- website
- Published by Wiley in Haemophilia
- Vol. 9 (4) , 348-352
- https://doi.org/10.1046/j.1365-2516.2003.00767.x
Abstract
Summary. In the clinical setting, patients suffering from haemophilia are classified according to the residual level of the deficient coagulation factor. Patients suffering from the severe form of haemophilia (critical factor level 0.50 IU mL−1 of FVIII to achieve a normal whole blood clotting profile. In conclusion, our study revealed that severe haemophilia A seems not to be a single entity, but rather several different clinical and biochemical phenotypes, and that the response to added FVIII varies amongst patients.Keywords
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