The Lethal Effects of Alpha Irradiation on Wild-Type and on a High-Catalase Mutant of Rheudopseudomonas spheroides
- 1 December 1962
- journal article
- research article
- Published by JSTOR in Radiation Research
- Vol. 17 (6) , 839-+
- https://doi.org/10.2307/3571316
Abstract
Wild type Rhodopseudomonas spheroides and a high-catalase mutant were studied with regard to the lethal actions of a-particles from radon and of reagent H2O2. The catalase of the mutant affords marked protection against H2O2 but not against a-particles. The killing by a-irradiation was not changed materially by altering the cell suspension density or by the presence of oxygen during irradiation. Application of target theory indicates that a cell loses viability if any part of it is intersected by the track of an a-particle. Exposure of wild-type R. spheroides cells to externally applied 1 M H2O2 for 30 seconds reduces the viable count by 50%. It is concluded that H2O2 in its ground state does not play a significant part in mediating the lethal action of a-particles on R. spheroides.This publication has 1 reference indexed in Scilit:
- The induced synthesis of catalase in Rhodopseudomonas spheroidesBiochimica et Biophysica Acta, 1959