Immunohistochemical Detection of Virulence-associated Antigens of Rhodococcus equi in Pulmonary Lesions of Foals
Open Access
- 1 May 1996
- journal article
- case report
- Published by SAGE Publications in Veterinary Pathology
- Vol. 33 (3) , 341-343
- https://doi.org/10.1177/030098589603300312
Abstract
Rhodococcus equi was isolated from the lungs of six foals with bronchopneumonia. All isolates expressed 15-17-kd antigens by immunoblot analysis and contained a virulence-associated plasmid of 85 or 90 kb. Immunohistochemically, R. equi from all pulmonary lesions showed the expression of 15-17-kd antigens mainly in the phagocytic cells. The specific monoclonal antibody to 15-17-kd antigens of R. equi (MAb 10G5) may be an aid in the diagnosis of R. equi-induced pneumonia.Keywords
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