An Overactivated ATR/CHK1 Pathway Is Responsible for the Prolonged G2 Accumulation in Irradiated AT Cells
Open Access
- 1 August 2003
- journal article
- Published by Elsevier
- Vol. 278 (33) , 30869-30874
- https://doi.org/10.1074/jbc.m301876200
Abstract
No abstract availableKeywords
This publication has 53 references indexed in Scilit:
- Caffeine-Induced Radiosensitization is Independent of Nonhomologous End Joining of DNA Double-Strand BreaksRadiation Research, 2003
- DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociationNature, 2003
- Ku affects the ATM-dependent S phase checkpoint following ionizing radiationOncogene, 2002
- BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damageNature Genetics, 2002
- Involvement of Brca1 in S-Phase and G2-Phase Checkpoints after Ionizing IrradiationMolecular and Cellular Biology, 2001
- The Radioresistance to Killing of A1–5 Cells Derives from Activation of the Chk1 PathwayPublished by Elsevier ,2001
- Caffeine Abolishes the Mammalian G2/M DNA Damage Checkpoint by Inhibiting Ataxia-Telangiectasia-mutated Kinase ActivityJournal of Biological Chemistry, 2000
- Review: ATM: the protein encoded by the gene mutated in the radiosensitive syndrome ataxia-telangiectasiaInternational Journal of Radiation Biology, 1999
- Defect in Multiple Cell Cycle Checkpoints in Ataxia-Telangiectasia PostirradiationPublished by Elsevier ,1996
- X-ray-induced G2 arrest in ataxia telangiectasia lymphoblastoid cellsMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1989