WORK PERFORMANCE OF HYPOPHYSECTOMIZED RATS TREATED WITH ANTERIOR PITUITARY EXTRACTS

Abstract
The work performance of hypophysectomized rats is greatly decreased. The work performance of hypophysectomized rats treated with growth, mammo-tropic and thyrotropic extracts is definitely improved. Hypophysectomized rats treated with adrenocorticotropic hormone show a greater improvement in work capacity than those treated with other pituitary extracts, and compare favorably with those treated with cortin. The work capacity of hypophysectomized, adrenalectomized rats maintained with cortin is not improved by the administration of adrenocorticotropic extracts. The work capacity of hypophysectomized rats treated with any of the ant. pituitary extracts is less than normal.

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