Successful management of congenital protein C deficiency with recurrent pregnancy loss
- 1 August 1995
- journal article
- case report
- Published by Wiley in International Journal of Gynecology & Obstetrics
- Vol. 50 (2) , 185-187
- https://doi.org/10.1016/0020-7292(95)02425-c
Abstract
A 29-year-old woman experienced unexplained intrauterine fetal death (IUFD) three times, at 16, 27 and 27 gestational weeks. She was found to be protein C-deficient and the existence of infarction in the placenta was suspected at 20 weeks' gestation during her fourth pregnancy. Both heparin and antithrombin III were administered until delivery of a small-for-dates but live baby. Massive infarction in the placenta was evident at term. Anticoagulation with heparin is a useful treatment approach for cases of recurrent IUFD with protein C deficiency.Keywords
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