Intracranial Pressure in Conscious Rabbits after Decentralization of the Superior Cervical Sympathetic Ganglia

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Abstract
The intracranial pressure, measured as the ventricular fluid pressure, was recorded continuously during about 2 days in conscious rabbits at various time‐periods after bilateral decentralization (preganglionic denervation) of the superior cervical sympathetic ganglia. The pressure recorded 5 h after the operation was initially unchanged compared with non‐denervated control animals. During the following day it increased by approximately 50 mm physiological saline. The pressure was elevated (by approximately 25 mm saline) also 6 days after the operation. At 2 weeks it had returned to almost the same level as in the non‐denervated controls. It is suggested that the alterations in the ventricular fluid pressure mainly reflect changes in the cerebral blood volume, although direct effects on the sympathetically supplied choroid plexuses cannot be excluded.

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