Proportions of Mitotic and Apoptotic Cells In A Range of Untreated Experimental Tumours
- 1 January 1988
- journal article
- research article
- Published by Wiley in Cell Proliferation
- Vol. 21 (1) , 45-49
- https://doi.org/10.1111/j.1365-2184.1988.tb00770.x
Abstract
The quantitative aspect of apoptosis in experimental tumors is often neglected. In this study, the apoptotic and mitotic indices for a range of tumors have been determined at light microscope level. It has been found that the apoptotic levels fall into a consistent range for all tumor types and agree well with those described by previous workers. It is suggested that these might be basic parameters of tumor expansion, as relevant to growth kinetics as mitotic levels.This publication has 9 references indexed in Scilit:
- Apoptosis: Cell death in tissue regulationThe Journal of Pathology, 1987
- Kinetic studies on a murine sarcoma and an analysis of apoptosisBritish Journal of Cancer, 1986
- A methacrylate embedding technique for combined autoradiography and acid phosphatase histochemistryJournal of Molecular Histology, 1985
- Cell death: a new classification separating apoptosis from necrosisPublished by Springer Nature ,1981
- An electron‐microscope study of the mode of cell death induced by cancer‐chemotherapeutic agents in populations of proliferating normal and neoplastic cellsThe Journal of Pathology, 1975
- The spontaneous occurrence of apoptosis in squamous carcinomas of the uterine cervixPathology, 1973
- Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue KineticsBritish Journal of Cancer, 1972
- A suggested explanation for the paradoxically slow growth rate of basal‐cell carcinomas that contain numerous mitotic figuresThe Journal of Pathology, 1972
- Shrinkage necrosis: A distinct mode of cellular deathThe Journal of Pathology, 1971