Stereoselective Reduction of Bicyclic Ketals. An Efficient Synthesis of (−)-(R,R)-(cis-6-Methyltetrahydropyran-2-yl)acetic Acid, an Enantiomer of Civet Cat Constituent
- 5 June 1988
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 17 (6) , 927-930
- https://doi.org/10.1246/cl.1988.927
Abstract
(−)-(R,R)-(cis-6-Methyltetrahydropyran-2-yl)acetic acid, an enantiomer of civet cat constituent, was prepared in high yield by using a stereoselective reduction of bicyclic ketals as a key step.Keywords
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