A Comparison of Adhesives Useable in the Cold for the Preparation of Cryostat Sections

Abstract
A variety of adhesives were used at —20 C to attach cryostat sections to cold slides and to allow fixation in the cryostat, thus preventing thawing artefacts. Of a range of adhesives readily available, a natural rubber solution, Romac C33, was found to give optimal results when used at this temperature. By this method histological, histochemical and immunofluorescent techniques could be successfully applied.