A one-step extraction and clean-up procedure before gas-liquid chromatographic determination of some organochlorine pesticide residues in blood
- 1 January 1968
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in The Analyst
- Vol. 93 (1108) , 445-452
- https://doi.org/10.1039/an9689300445
Abstract
An apparatus and a method are described for the extraction and clean-up of organochlorine pesticides, e. g., DDT, DDE, α-and γ-BHC (lindane) and dieldrin, from heparin-treated and lyophilised blood samples for gas-chromatographic determinations. Extraction and clean-up are carried out in one step on a suitable column with amounts of solvent as small as 25 to 30 ml. Two types of column are used according to the type of organochlorine pesticide to be determined; for acid-stable substances a sulphuric acid-diatomaceous earth column is used, and for alkali-stable pesticides an alkaline column, on which saponification of fat takes place simultaneously with extraction. The method has been applied successfully in worker as well as in general population surveys.Keywords
This publication has 0 references indexed in Scilit: