Proximal myopathy caused by latrogenic phosphate depletion
- 20 September 1976
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 236 (12) , 1380-1381
- https://doi.org/10.1001/jama.236.12.1380
Abstract
Severe proximal myopathy associated with hypophosphatemia developed in three patients with chronic renal failure who had been treated with aluminum hydroxide gel. The syndrome was characterized by severe pain, muscular stiffness, and weakness. The illness was originally misdiagnosed both as uremic myopathy and as an exacerbation of rheumatoid arthritis. In one patient, the correct diagnosis was made when symptomatic relief corresponded to the rise of serum phosphate levels. Discontinuation of antacid therapy was followed by gradual recovery. Oral sodium phosphate brought prompt alleviation of muscular pain and stiffness. (JAMA236:1380-1381, 1976)This publication has 1 reference indexed in Scilit:
- Skeletal Resistance to Parathyroid Hormone in Renal FailureAnnals of Internal Medicine, 1973