Shhh! Silencing by microRNA-155
- 13 November 2008
- journal article
- review article
- Published by The Royal Society in Philosophical Transactions Of The Royal Society B-Biological Sciences
- Vol. 364 (1517) , 631-637
- https://doi.org/10.1098/rstb.2008.0209
Abstract
Small RNAs mediate a diverse pot-pourri of post-transcriptional silencing mechanisms, ranging from 'classical' RNA interference (RNAi), to gene repression by microRNAs (miRNAs), to maintenance of genomic stability by repeat-associated small RNAs. Here, we review recent findings on the function of miR-155, particularly its roles in mammalian innate and adaptive immunity, viral infection and oncogenesis.Keywords
This publication has 80 references indexed in Scilit:
- Viral and Cellular MicroRNAs as Determinants of Viral Pathogenesis and ImmunityCell Host & Microbe, 2008
- MicroRNA-155 Suppresses Activation-Induced Cytidine Deaminase-Mediated Myc-Igh TranslocationImmunity, 2008
- MicroRNA-155 Is a Negative Regulator of Activation-Induced Cytidine DeaminaseImmunity, 2008
- A viral microRNA functions as an orthologue of cellular miR-155Nature, 2007
- RNA catalysis: ribozymes, ribosomes, and riboswitchesPublished by Elsevier ,2007
- Antiviral Immunity Directed by Small RNAsCell, 2007
- A Mammalian microRNA Expression Atlas Based on Small RNA Library SequencingCell, 2007
- BIC and miR‐155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomasThe Journal of Pathology, 2005
- Combinatorial microRNA target predictionsNature Genetics, 2005
- Prediction of Mammalian MicroRNA TargetsCell, 2003