More on Chewing the Fat

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Abstract
In the report by McMurry et al. in this issue of the Journal,1 native Mexicans who traditionally consume little fat were given a diet that, even by U.S. standards, was high in animal fat. Serum total cholesterol levels rose, but so did those of high-density lipoprotein (HDL) cholesterol; the ratio of total to HDL cholesterol or of low-density lipoprotein (LDL) to HDL cholesterol changed minimally. The reverse is often seen among patients who adopt a low-fat diet. In a typical example, total cholesterol may decrease markedly, from 260 to 210 mg per deciliter (6.7 to 5.4 mmol per liter), . . .

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