Inhibition of Dietary Hypercholesteremia and Atherogenesis in the Chicken by a New Synthetic Compound
- 1 May 1958
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 6 (3) , 260-265
- https://doi.org/10.1161/01.res.6.3.260
Abstract
Addition of 0.1 per cent MER-13 to an atherogenic, high-cholesterol diet largely prevented the development of hypercholesteremia and aortic and coronary artery atheromatosis in cockerels. The hypocholesteremic effect was not obtained when MER-13 was administered following the removal of cholesterol from the diet. It is concluded that MER-13 inhibits absorption of cholesterol from the gastrointestinal tract.Keywords
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