EXPERIMENTAL STUDIES ON EARLY LENS CHANGES AFTER ROENTGEN IRRADIATION

1 February 1951

journal article
research article
Published by American Medical Association (AMA) in A.M.A. Archives of Ophthalmology

Vol. 45 (2) , 149-164
https://doi.org/10.1001/archopht.1951.01700010154003

Abstract

SINCE it was first shown that roentgen ray cataract could be produced experimentally in mature animals (in guinea pigs by Bossuet,¹in 1909, and in rabbits by Aulamo,²in 1928), the question of the primary site of radiation injury to the lens and the pathogenesis of the lesion have been discussed by many investigators on the basis of experimental and clinical evidence and have been studied systematically by a few. Most investigators have favored the concept of direct radiation damage to the lens (Bossuet,¹Politzer,³Rohrschneider,⁴Peter,⁵Grzedzielski,⁶Okusawa,⁷Leinfelder and Kerr,⁸Goldmann and Liechti,⁹von Szily,¹⁰Krückmann,¹¹Poppe¹²), whereas others, on the basis of the clinical characteristics of the cataract, have preferred the hypothesis of an indirect radiation effect induced by damage to the structures of the ciliary processes, with consequent nutritional disturbance of the lens

Keywords

This publication has 1 reference indexed in Scilit:

The Nature of the Specificity of Methyl Green for Chromatin
Proceedings of the National Academy of Sciences, 1949