Translational Bioinformatics: Coming of Age
Open Access
- 1 November 2008
- journal article
- Published by Oxford University Press (OUP) in Journal of the American Medical Informatics Association
- Vol. 15 (6) , 709-714
- https://doi.org/10.1197/jamia.m2824
Abstract
The American Medical Informatics Association (AMIA) recently augmented the scope of its activities to encompass translational bioinformatics as a third major domain of informatics. The AMIA has defined translational bioinformatics as “… the development of storage, analytic, and interpretive methods to optimize the transformation of increasingly voluminous biomedical data into proactive, predictive, preventative, and participatory health.” In this perspective, I will list eight reasons why this is an excellent time to be studying translational bioinformatics, including the significant increase in funding opportunities available for informatics from the United States National Institutes of Health, and the explosion of publicly-available data sets of molecular measurements. I end with the significant challenges we face in building a community of future investigators in Translational Bioinformatics.Keywords
This publication has 33 references indexed in Scilit:
- The Ultimate Model OrganismScience, 2008
- Evaluation and integration of 49 genome-wide experiments and the prediction of previously unknown obesity-related genesBioinformatics, 2007
- The NCBI dbGaP database of genotypes and phenotypesNature Genetics, 2007
- The minimum information about a proteomics experiment (MIAPE)Nature Biotechnology, 2007
- NCBI GEO: mining tens of millions of expression profiles--database and tools updateNucleic Acids Research, 2006
- [9] TM4 Microarray Software SuitePublished by Elsevier ,2006
- GenePattern 2.0Nature Genetics, 2006
- GenMAPP, a new tool for viewing and analyzing microarray data on biological pathwaysNature Genetics, 2002
- Significance analysis of microarrays applied to the ionizing radiation responseProceedings of the National Academy of Sciences, 2001
- Distinct types of diffuse large B-cell lymphoma identified by gene expression profilingNature, 2000