REGENERATION OF MYOCARDIAL-CELLS - OBSERVATION IN ANEURYSMECTOMIZED VENTRICULAR WALL

  • 1 January 1984
    • journal article
    • research article
    • Vol. 108  (4) , 287-292
Abstract
A small necrotic focus with regeneration of myocardial cells in an aneurysmectomized ventricular wall was observed in a 46-yr-old man. Marginating the area of necrosis were myocardial cells with mitosis, with frequent multinucleated and binucleated cells. In the area of necrosis, there was a proliferation of many round, oval to polygonal cells with a high mitotic activity. These cells had eosinophilic granular cytoplasm and one prominent nucleus. Some cells were solitary while others clustered in and around the damaged myocardial fibers. Some cells formed a syncytium and were attached to the perimysial tubes with protoplasmic extensions. These proliferated cells are believed to be a single-cell line and to originate from the damaged myocardial cells. Human myocardial cells may regenerate continuously from surviving myocardial cells and proliferate discontinuouosly.