Leukocyte Alkaline Phosphatase: Electrophoretic Variants Associated with Chronic Myelogenous Leukemia
- 1 October 1965
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 150 (3692) , 58-60
- https://doi.org/10.1126/science.150.3692.58
Abstract
Starch-gel electrophoresis of leukocyte alkaline phosphatases, rendered soluble by treating normal leukocytes with butanol, revealed three electrophoretic variants of the enzyme. The phosphatases in similarly prepared extracts of leukemia cells differed from the normal isozymes in electrophoretic. mobility. A single variant was detected in one case of untreated leukemia; a similar component and three additional ones were seen in leukemia treated with 6-mercaptopurine.This publication has 7 references indexed in Scilit:
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