Aging, Progenitor Cell Exhaustion, and Atherosclerosis
Top Cited Papers
- 29 July 2003
- journal article
- Published by Wolters Kluwer Health in Circulation
- Vol. 108 (4) , 457-463
- https://doi.org/10.1161/01.cir.0000082924.75945.48
Abstract
Background— Atherosclerosis is largely attributed to chronic vascular injury, as occurs with excess cholesterol; however, the effect of concomitant vascular aging remains unexplained. We hypothesize that the effect of time in atherosclerosis progression is related to obsolescence of endogenous progenitor cells that normally repair and rejuvenate the arteries.Keywords
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