Potent and Selective Cathepsin L Inhibitors Do Not Inhibit Human Osteoclast Resorption in Vitro
Open Access
- 1 April 2001
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 276 (15) , 11507-11511
- https://doi.org/10.1074/jbc.m010684200
Abstract
No abstract availableKeywords
This publication has 19 references indexed in Scilit:
- Cathepsin K Knockout Mice Develop Osteopetrosis Due to a Deficit in Matrix Degradation but Not DemineralizationJournal of Bone and Mineral Research, 1999
- Synthesis of Peptide Aldehyde Derivatives as Selective Inhibitors of Human Cathepsin L and Their Inhibitory Effect on Bone ResorptionJournal of Medicinal Chemistry, 1998
- Peptide Aldehyde Inhibitors of Cathepsin K Inhibit Bone Resorption Both In Vitro and In VivoJournal of Bone and Mineral Research, 1997
- Pycnodysostosis, a Lysosomal Disease Caused by Cathepsin K DeficiencyScience, 1996
- Cathepsin K, but Not Cathepsins B, L, or S, Is Abundantly Expressed in Human OsteoclastsJournal of Biological Chemistry, 1996
- Suppressive effect of N-(benzyloxycarbonyl)-l-phenylalanyl-l-tyrosinal on bone resorption in vitro and in vivoEuropean Journal of Pharmacology, 1996
- Cell-mediated extracellular acidification and bone resorption: evidence for a low pH in resorbing lacunae and localization of a 100-kD lysosomal membrane protein at the osteoclast ruffled border.The Journal of cell biology, 1985
- Investigation of cell lineage in bone using a chimaera of chick and quail embryonic tissueNature, 1975
- Osteopetrosis Cured by Temporary ParabiosisScience, 1973
- Pycnodysostosis, with a familial chromosome anomalyThe American Journal of Medicine, 1966