FIELD-TEST AND EXPERIMENTAL USE OF CYBEST MODEL 2 FOR PRACTICAL GYNECOLOGIC MASS-SCREENING

Google Scholar
  • 1 January 1979
    • journal article
    • research article
    • Vol. 1  (2) , 122-126
Abstract
CYBEST is an automated cytologic screening system for uterine cancer utilizing a pattern-recognition image-analysis system. The prototype was developed in 1972 following fundamental studies of feature extraction, feature evaluation using ambiguity differential functions and segmentation of cell and nuclear images. Model 2 was developed in 1974 with an improved mechanism and function. The parameters employed are nuclear size, nuclear optical density, N/C ratio and nuclear shape. The data of field tests using 220 samples containing 3 cases of dysplasia, 110 cases of carcinoma and 107 nonmalignant cases were as follows: 2 false-negative cases (1.8%), 13 false positives (12.1%) and 1 reject (0.9%). This system was experimentally tested for practical mass population screening with 1829 cases including 17 atypical cases (4 epidermoid carcinomas). The data were as follows: no false-negative cases and 581 false-positive cases (32.1%). Of the latter, 311 cases (17.2%) were pathologic samples, such as severe cervicitis, senile colpitis, Trichomonas infestation, etc., and the remaining 270 cases (14.9%) were within physiologic limits, corresponding to true false-positive samples.