Dual Role of Diffusion in Tissue Gas Exchange: Blood-Tissue Equilibration and Diffusion Shunt
- 1 January 1984
- book chapter
- Published by Springer Nature
- Vol. 180, 85-94
- https://doi.org/10.1007/978-1-4684-4895-5_7
Abstract
In a previous study the washout kinetics of two inert gases of different diffusivity, methane (CH4) and sulfur hexafluoride (SF6), was found to be incompatible with the assumption of exclusive perfusion limitation (Piiper and Meyer, in press). Also models with additional tissue-blood diffusion limitation could not explain the experimental findings. Only a model incorporating veno-arterial back diffusion appeared to provide a satisfactory agreement between model predictions and experimental data.Keywords
This publication has 6 references indexed in Scilit:
- Model for capillary-alveolar equilibration with special reference to O2 uptake in hypoxiaPublished by Elsevier ,2003
- Cerebral gas exchange: perfusion and diffusion limitationsJournal of Applied Physiology, 1979
- Is inert gas washout from the tissues limited by diffusion?Journal of Applied Physiology, 1978
- Determination of local blood flow (microflow) by electrochemically generated hydrogenPflügers Archiv - European Journal of Physiology, 1974
- A rebreathing method for estimating pulmonary Do2: Theory and measurements in dog lungsRespiration Physiology, 1973
- MEASUREMENT OF BLOOD-FLOW THROUGH SKELETAL MUSCLE BY INTRAMUSCULAR INJECTION OF XENON-133The Lancet, 1964