Accumulation of Foam Cells in Liver X Receptor-Deficient Mice
- 27 August 2002
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 106 (9) , 1147-1153
- https://doi.org/10.1161/01.cir.0000026802.79202.96
Abstract
Background— The nature of some of the target genes for liver X receptors (LXRs)-α and -β, such as sterol regulatory element binding protein-1 and ATP-binding cassette transporter proteins, suggests...Keywords
This publication has 19 references indexed in Scilit:
- Hepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDLJournal of Clinical Investigation, 2001
- Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRβ-deficient miceJournal of Clinical Investigation, 2001
- AtherosclerosisCell, 2001
- Thyroid Hormone Stimulates Acetyl-CoA Carboxylase-α Transcription in Hepatocytes by Modulating the Composition of Nuclear Receptor Complexes Bound to a Thyroid Hormone Response ElementJournal of Biological Chemistry, 2001
- Functional Loss of ABCA1 in Mice Causes Severe Placental Malformation, Aberrant Lipid Distribution, and Kidney Glomerulonephritis As Well As High-Density Lipoprotein Cholesterol DeficiencyThe American Journal of Pathology, 2000
- Transport of lipids from Golgi to plasma membrane is defective in Tangier disease patients and Abc1-deficient miceNature Genetics, 2000
- Immunoglobulin treatment reduces atherosclerosis in apo E knockout mice.Journal of Clinical Investigation, 1998
- A mouse model of human familial hypercholesterolemia: Markedly elevated low density lipoprotein cholesterol levels and severe atherosclerosis on a low-fat chow dietNature Medicine, 1998
- Impaired secretion of very low density lipoprotein-triglycerides by apolipoprotein E- deficient mouse hepatocytes.Journal of Clinical Investigation, 1997
- Altered Lipid Metabolism in Apolipoprotein E-Deficient Mice Does Not Affect Cholesterol Balance Across the LiverHepatology, 1996