Transepithelial sodium transport and carbon dioxide production by the toad urinary bladder in the absence of serosal sodium.

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Abstract
The production of CO2 in relation to Na transport by toad urinary bladder was examined in the absence of Na from the serosal medium. Replacement of serosal Na by choline increased CO2 production without stimulating short-circuit current. Replacement of serosal medium by Tris did not have this effect. With serosal sodium Ringer replaced by Tris Ringer, the ratio of Na transported to CO2 produced was not altered significantly. There was no important recycling of Na between the serosal medium and the transporting epithelial cells.