An Approach to the Precise Chemoenzymatic Synthesis of 13C-Labeled Sialyloligosaccharide on an Intact Glycoprotein: A Novel One-Pot [3-13C]-Labeling Method for Sialic Acid Analogues by Control of the Reversible Aldolase Reaction, Enzymatic Synthesis of [3-13C]-NeuAc-α-(2→3)-[U-13C]-Gal-β-(1→4)-GlcNAc-β- Sequence onto Glycoprotein, and Its Conformational Analysis by Developed NMR Techniques
- 31 May 2000
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 122 (24) , 5678-5694
- https://doi.org/10.1021/ja994211j
Abstract
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This publication has 76 references indexed in Scilit:
- Chemoenzymatic Synthesis of the 9-Deoxy- 9-fluoro-[3-13C]-NeuAc-α-(2→6)-[U-13C]-Gal-β- Sequence on an Intact GlycoproteinJournal of the American Chemical Society, 1999
- Bioaffinity NMR Spectroscopy: Identification of an E-Selectin Antagonist in a Substance Mixture by Transfer NOEAngewandte Chemie International Edition in English, 1999
- Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigmCell, 1994
- Sialic acids as important molecules in the regulation of the immune system: pathophysiological implications of sialidases in immunityGlycobiology, 1993
- Semianalytical treatment of solvation for molecular mechanics and dynamicsJournal of the American Chemical Society, 1990
- GLYCOBIOLOGYAnnual Review of Biochemistry, 1988
- N-Acetyl-4-deoxy-d-neuraminic acid is activated and transferred on to asialoglycoproteinGlycoconjugate Journal, 1987
- Preparation of 9‐fluoro‐9‐deoxy‐N‐[2‐14C]acetylneuraminic acidFEBS Letters, 1984
- Carbon-13 nuclear magnetic resonance of ganglioside sugars. Spin-lattice relaxation probes for structure and microdynamics of cell surface carbohydratesJournal of the American Chemical Society, 1977
- 13C Spin‐Lattice Relaxation Times and the Mobility of Organic Molecules in SolutionAngewandte Chemie International Edition in English, 1975