Experimental elastosis induced by chronic ultraviolet exposure
- 1 October 1980
- journal article
- research article
- Published by Springer Nature in Archives of Dermatological Research
- Vol. 269 (1) , 39-49
- https://doi.org/10.1007/bf00404456
Abstract
The effect of long-term ultraviolet irradiation on the connective tissue of the skin was investigated in 25 naked (Ng/-) mice which received a total daily radiant dose of 40±2 J/cm2 for a period of 8.5 months. The produced alterations were very similar to those found in actinic elastosis of humans, as assessed by histologic and electron-microscopic criteria. Der Einfluß chronischer UV-Lichteinwirkung auf das dermale Bindegewebe der Nacktmaus (Ng/-) wurde licht- und elektronenmikroskopisch untersucht (25 Tiere; Dauer der Bestrahlung 8,5 Monate; tägliche Strahlendosis 40±2 J/cm2). Die induzierten Bindegewebsveränderungen entsprechen weitgehend dem Bild, wie es bei der menschlichen aktinischen Elastose angetroffen wird.Keywords
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