Griseofulvin treatment in experimentalMicrosporum canisinfection in the cat

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Abstract
Orally administered griseofulvin caused Microsporum canis infection to disappear from within the hair follicles in artificially infected cats. At the same time, clinical evidence of infection also disappeared although fluorescence persisted. Removal of the distal part of affected hairs in conjunction with the application of an anti-fungal preparation reduced the period of positive fluorescence and of the recovery of the fungus in culture. La griséofulvine administrée par voie orale provoque la disparition de M. canis des folicules pileux de chats expérimentalement infectés. Les manifestations cliniques disparaissent également bien que la fluorescence des poils persiste. En coupant la partie distale des poils infectés et en appliquant une préparation antifongique on réduit la période de temps pendant laquelle s'observe la fluorescence et s'obtiennent les cultures du parasite.

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