CORRELATION OF ELISA-DETECTED IgG AND IgA ANTI-HLA ANTIBODIES IN PRETRANSPLANT SERA WITH RENAL ALLOGRAFT REJECTION1

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Abstract
The present study compared the occurrence of rejection episodes during the first twelve posttransplant (Tx) months and the 1-, 2-, and 3-year graft survivals among recipients stratified by the percent panel reactive antibody (% PRA) of pre-Tx sera as detected using either an antihuman globulin determined PRA (AHG-% PRA) or an ELISA methodology detecting IgG reactive against soluble HLA class I antigens (% PRA-STAT). There was a significant correlation between AHG-PRA≥10% and a PRA-STAT≥10% (P