Clinical Strain of Pseudomonas aeruginosa Carrying a bla TEM-21 Gene Located on a Chromosomal Interrupted Tn A Type Transposon

Abstract
A clinical isolate of Pseudomonas aeruginosa was found to produce a clavulanic acid-inhibited extended-spectrum β-lactamase with a pI of 6.4. PCR, cloning, and sequencing experiments showed that the corresponding bla TEM-21 gene was part of a chromosomally located Tn 801 transposon disrupted by an IS 6100 element and adjacent to an aac(3)-II gene.