Effect of Mycobacterium phleiupon Reticuloendothelial System of Mice of Different Ages

1 March 1963

journal article
research article
Published by Frontiers Media SA in Experimental Biology and Medicine

Vol. 112 (3) , 651-654
https://doi.org/10.3181/00379727-112-28129

Abstract

Summary A single intravenous injection of Mycobacterium phlei Halpern into mice (1 to 12 months old) elicited a bimodal stimulation of global phagocytic activity. The liver and spleen became enlarged, but returned to normal size after about 2 months. A simple formula was developed for rating the efficiency of the phagocytic organs of mice by taking into account the hepatosplenomegaly accompanying RES stimulation.

Keywords

This publication has 3 references indexed in Scilit:

THE RETICULOENDOTHELIAL SYSTEM AND THE NEOPLASTIC PROCESS*
Annals of the New York Academy of Sciences, 1960
THE RETICULOENDOTHELIAL SYSTEM AND NONSPECIFIC RESISTANCE
Annals of the New York Academy of Sciences, 1960
THE EFFECT OF BACTERIAL CONSTITUENTS ON THE RESISTANCE OF MICE TO HETEROLOGOUS INFECTION AND ON THE ACTIVITY OF THEIR RETICULO-ENDOTHELIAL SYSTEM
The Journal of Experimental Medicine, 1958