Confirmation of conductance increase by adrenalin in the guinea-pig taenia coli (α-action)

Publisher Website
Google Scholar
Abstract
In the guinea-pig tenia coli, adrenaline [epinephrine] hyperpolarized the membrane and decreased the amplitude of electrotonic potentials when recorded with microelectrodes from the center pool (500 .mu.m in width) of the double sucrose-gap apparatus. The reduction of the time constant of electrotonic potentials was proportional to that of the amplitude, indicating that the membrane capacity remained constant. The tissue impedance, measured by sinusoidal currents with a frequency range of 0.1-50 Hz, also indicated that the decrease of membrane resistance by adrenaline was accompanied by little change in the membrane capacity.