Effect of Tetraethylammonium on Venous and Arterial Pressure in Congestive Heart Failure.

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Abstract
Tetraethylammonium chloride given intraven. to 9 normotensive patients in congestive heart failure caused a precipitous fall in peripheral venous pressure and a significant decrease in arterial pressure in every case. Compensated cardiacs and non-cardiac normotensive controls showed no fall in venous pressure and a smaller change in arterial pressure. Because the chief action of tetraethylammonium is to block the peripheral autonomic ganglia, these data imply the existence of increased autonomic vascular tone in congestive heart failure.