Peroxidase Mediated Antimicrobial Activities of Alveolar Macrophage Granules

31 August 1973

journal article
other
Published by American Association for the Advancement of Science (AAAS) in Science

Vol. 181 (4102) , 849-850
https://doi.org/10.1126/science.181.4102.849

Abstract

The 20,000g pellet obtained by centrifugation of a homogenate of rabbit alveolar macrophages has antibacterial activity in the presence of a hydrogen peroxide-generating system and iodide. Peroxidase activity has been demonstrated in this fraction. Addition of 3-amino-1,2,4-triazole diminished the antibacterial activity of the pellet-hydrogen peroxide-iodide system.

Keywords

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