Progression of Mild Cognitive Impairment to Dementia in Clinic- vs Community-Based Cohorts
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Open Access
- 1 September 2009
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 66 (9) , 1151-1157
- https://doi.org/10.1001/archneurol.2009.106
Abstract
The term mild cognitive impairment (MCI) has been used to describe the transition between normal cognition and Alzheimer dementia.1,2 Mild cognitive impairment is recognized as an important public health problem as a dementia risk. Annual conversion rates often range from 10% to 15% in clinic samples.3-5 Conversion rates in community-based studies are often substantially lower (ie, 3.8%-6.3% per year6-9). Mild cognitive impairment is also less stable in community samples.8,10,11 Clearly patients with MCI compose a heterogeneous group, of whom not all rapidly convert to dementia. As such, it is important to identify risk factors for progressing rapidly among individuals diagnosed with MCI.Keywords
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