Temperature dependence of the ionic current kinetics of Myxicola giant axons

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Abstract
1. The temperature dependence of the sodium and potassium conductances of Myxicola giant axons was studied in the range of 1-18 degrees C.2. Analysis of voltage clamp records for step depolarizations of 20-150 mV yielded Q(10)'s for g(Na), g(K), and g(1) of 1.3-1.5. The steady-state parameters m(infinity) (v), n(infinity) (v) were independent of temperature. The time constants had Q(10)'s of: 2.64 +/- 0.2 for tau(m); 2.56 +/- 0.2 for tau(h); 3.02 +/- 0.3 for tau(n).3. tau(h) determined from the effects of prepulse duration rather than the decline in sodium current during a step depolarization had a Q(10) of 2.47 +/- 0.2.