A mutation in the GABAA receptor α1 subunit linked to human epilepsy affects channel gating properties
- 30 April 2004
- journal article
- Published by Elsevier in Neuropharmacology
- Vol. 46 (5) , 629-637
- https://doi.org/10.1016/j.neuropharm.2003.11.015
Abstract
No abstract availableKeywords
This publication has 35 references indexed in Scilit:
- Altered kinetics and benzodiazepine sensitivity of a GABA A receptor subunit mutation [γ 2 (R43Q)] found in human epilepsyProceedings of the National Academy of Sciences, 2002
- Two Different Mechanisms of Disinhibition Produced by GABAAReceptor Mutations Linked to Epilepsy in HumansJournal of Neuroscience, 2002
- Mutation of GABRA1 in an autosomal dominant form of juvenile myoclonic epilepsyNature Genetics, 2002
- Agonist Trapping by GABAAReceptor ChannelsJournal of Neuroscience, 2001
- First genetic evidence of GABAA receptor dysfunction in epilepsy: a mutation in the γ2-subunit geneNature Genetics, 2001
- θ, a novel γ-aminobutyric acid type A receptor subunitProceedings of the National Academy of Sciences, 1999
- Binding, gating, affinity and efficacy: The interpretation of structure‐activity relationships for agonists and of the effects of mutating receptorsBritish Journal of Pharmacology, 1998
- Role of the Putative Transmembrane Segment M3 in Gating of Neuronal Nicotinic ReceptorsBiochemistry, 1997
- Selective isolation of transiently transfected cells from a mammalian cell population with vectors expressing a membrane anchored single-chain antibodyJournal of Immunological Methods, 1996
- Assembly of GABAA receptor subunits: analysis of transient single-cell expression utilizing a fluorescent substrate/marker gene techniqueJournal of Neuroscience, 1993