ON THE POSSIBLE INFLUENCE OF GREAT ALTITUDES ON THE DETERMINATION OF CERTAIN CARDIOVASCULAR ANOMALIES

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Abstract
Over a period of 8 years, 176 cases of cardiac anomalies have been found in over 10,000 consecutive admissions. The place of birth and its altitude have been recorded for each one of these causes. Patent ductus arteriosus and persistent interatrial communications are more likely to be found in patients born at high altitudes. It is suggested, but remains to be shown, that this is true for defects of the pulmonary artery. No apparent relation could be found in this series for other malformations. It is presumed that mechanical factors tied to the pulmonary circulation and the lower oxygen tension both have a decisive influence.

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