Fungal infections

Abstract
The number of effective chemotherapeutic agents presently available for serious mycotic infections is limited.5, 6 This is due in part to many problems encountered by both the basic scientist and the clinician, in the laboratory and clinical evaluation of such drugs. This report summarizes some of these problems particularly as they have affected our studies with such compounds as amphotericin B, flucytosine, hamycin, and clotrimazole.

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