A guanyloribonuclease of mouse liver cytosol

Abstract
The acid RNase activity of mouse liver cytosol has been resolved into two different enzymes named acid RNase I and acid RNase II respectively. Acid RNase I is a typical pancreatic‐type enzyme hydrolyzing CpN and UpN bonds. Acid RNase II, however, hydrolyzes GpN bonds in non‐hydrogen‐bonded regions of the substrate.